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Anemia Toolkit

Iron Deficiency and Reduced Work Capacity: A Critical Review of the Research to Determine a Causal Relationship

This systematic review synthesizes the evidence pertaining to the relationship between iron deficiency and physical work capacity in animals and humans. 
Evidence from 29 research reports demonstrates a strong causal effect of severe and moderate iron deficiency anemia on aerobic capacity in animals and humans, which is possibly due to 1) the reduced oxygen transport associated with anemia, or 2) tissue iron deficiency through reduced cellular oxidative capacity.
Anemia Toolkit

Prevention and Control of Iron Deficiency: Policy and Strategy Issues

This article highlights the lack of mechanisms at the country and global levels to ensure that effective measures for prevention and control of iron deficiency are implemented.
Anemia Toolkit

The Global Call to Action to Increase National Coverage of Intermittent Preventive Treatment of Malaria in Pregnancy for Immediate Impact

This document details a Global Call to Action from The Roll Back Malaria Partnership with an aim to increase national coverage with preventive treatment of malaria in pregnant women. The aim is to increase national coverage of intermittent preventive treatment of malaria in pregnancy for immediate impact.
Anemia Toolkit

Iron Bioavailability and Dietary Reference Values

This review describes the dietary and host factors that have been reported to influence iron bioavailability, and the process by which these factors have been used to establish iron bioavailability values for the estimation of dietary reference values, and the extent to which the bioavailability values could be refined further.
Anemia Toolkit

Late vs. Early Clamping of the Umbilical Cord in Full-Term Neonates: Systematic Review and Meta-Analysis of Controlled Trials

This systematic review synthesizes the evidence pertaining to benefits and risks with regard to timing of umbilical cord clamping in full-term neonates.
Anemia Toolkit

Interventional Strategies for Prevention of Nutritional Anemia

This book chapter discusses strategies for anemia prevention in children, including dietary approaches as well as prevention of diarrhea and helminth infection.
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Improving the Chances that Nutrient Supplements Will Make a Difference

This presentation highlights approaches aimed at improving demand for iron–folic acid supplementation and discusses how to support adherence during pregnancy.
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Translating Formative Research Findings into a Behaviour Change Strategy to Promote Antenatal Calcium and Iron and Folic Acid Supplementation in Western Kenya

This study involved in-depth interviews with 22 pregnant and postpartum women and 20 community-based and facility-based health workers in Kenya for the purposes of planning a calcium and iron–folic acid supplementation program. Interviews assessed awareness of anemia, preeclampsia, and eclampsia; ANC attendance; and barriers and facilitators to iron–folic acid supplement delivery and adherence.
Anemia Toolkit

The Importance and Limitation of Food Fortification for the Management of Nutritional Anemia

This book chapter highlights important considerations with regards to food fortification and how it can be used as an approach to managing nutritional anemias. The chapter highlights how food fortification can be leveraged and discusses limitations.
Anemia Toolkit

Maternal and Neonatal Outcomes Related to Iron Supplementation or Iron Status: A Summary of Meta-Analyses

This review was conducted to derive an umbrella summary of meta-analyses performed to evaluate the effects and associations of iron supplementation or iron status on maternal and birth/neonatal outcomes. Evidence from 16 meta-analyses suggests beneficial effects of multiple-micronutrient supplementation on some neonatal outcomes. Furthermore, higher ferritin levels seem to increase the risk for gestational diabetes mellitus, whereas maternal anemia was associated with adverse birth/neonatal outcomes.