Malaria is a leading cause of morbidity and mortality among children under 5 years and anemia is a well known morbidity resulting from malaria infection. This study in western Kenya found malaria infection significantly increased odds of risk for delays in gross motor, communication, and social-emotional development. Anemia was a significant mediator on the path between malaria infection and poor child development; however, the total effect of anemia was small (it explained only 9-16 percent of the risk), indicating the need for more research to understand the pathways between milder malaria infection and child development outcomes.