This Cochrane Systematic Review synthesizes the evidence pertaining to the impact of food fortification with multiple micronutrients on health outcomes in the general population, including men, women, and children. Evidence from 43 studies suggests that food fortification with multiple micronutrients may reduce anemia (by 32 percent), iron deficiency anemia (by 72 percent), as well as micronutrient deficiencies (including iron deficiency by 56 percent, vitamin A deficiency by 58 percent, vitamin B2 deficiency by 64 percent, vitamin B6 deficiency by 91 percent, and vitamin B12 deficiency by 58 percent). Fortification with multiple micronutrients may also improve child growth measured as weight for age and weight for height/length.