This compendium documents the collaborating, learning, and adapting (CLA) approaches implemented by USAID Advancing Nutrition. It also compiles internal resources and templates that we developed to support CLA implementation across the project (annex 1) and the project’s CLA plan (annex 2). The aim of this compendium is to share a practical example of how a global USAID project with core funding and 12 Mission buy-ins applied CLA from 2018–2023, generating lessons learned to improve implementation during the project period and to inform future nutrition projects. Other USAID investments can adapt and apply the approaches described, and resources and templates provided.