This report summarizes the achievements of the Nurturing Care Framework, including the development of new global measures for population-level assessments of early child development (ECD), an extensive research repository, and ECD profiles for 197 countries. Priorities include using new measures and locally generated evidence and data to inform policy, planning, budgeting, and financing, stimulating initiatives at subnational levels and in communities, strengthening systems capacity, and producing local evidence about interventions that improve ECD outcomes and reduce inequities.