In its first year, USAID Advancing Nutrition, the Agency’s flagship multi-sectoral nutrition project, co-developed a project-wide internal SBC Strategic Focus Document with nutrition SBC leads at the USAID Bureau for Resilience and Food Security (RFS), the Bureau for Global Health, and the Bureau for Humanitarian Assistance (BHA) to guide activities during the life of the project and help carry out the USAID Multi-Sectoral Nutrition Strategy. This document builds on that roadmap and experience and presents an updated strategic direction. As with the previous internal document, USAID nutrition SBC leads co-created this revised SBC Strategic Focus Document with project SBC staff. It outlines current challenges to quality nutrition SBC. It highlights nutrition SBC priorities common to USAID bureaus and describes why these are relevant and the expected results of achieving each. It also provides illustrative activities or ways that the new global USAID nutrition partner could address the area internal to the award and with external nutrition partners.